Efficacy and effect of Zhuanggu joint capsule?

summary

Zhuanggu joint capsule z20080055, Zhuanggu joint capsule, tonifying liver and kidney, nourishing and activating blood, relaxing channels and activating collaterals, regulating qi and relieving pain. It is used for degenerative osteoarthropathy and lumbar muscle strain caused by deficiency of liver and kidney, qi stagnation and blood stasis, obstruction of channels and collaterals. So, what is the price of Zhuanggu joint capsule? What is the function of Zhuanggu joint capsule

Efficacy and effect of Zhuanggu joint capsule?

The adverse reactions of Zhuanggu joint capsule included liver dysfunction, skin rash, pruritus, nausea, vomiting, abdominal pain, diarrhea, stomachache, high blood pressure and so on. Liver injury is mostly cholestatic hepatitis. The clinical manifestations of liver dysfunction are relatively consistent, mainly fatigue, anorexia, yellow urine, pruritus, pale stool color, and yellow sclera. Some cases (2 cases) have liver enlargement, and some cases have abnormal liver enzyme indexes. Therefore, the reported cases of adverse reactions after drug withdrawal, symptomatic treatment, the prognosis of patients is good.

Zhuanggujie capsule is used for tonifying liver and kidney, nourishing blood and activating blood, relaxing muscles and activating collaterals, regulating qi and relieving pain. It is used for degenerative osteoarthropathy and lumbar muscle strain caused by deficiency of liver and kidney, qi stagnation and blood stasis, obstruction of channels and collaterals. Zhuanggu jiejie pill and Zhuanggu jiejie capsule have similar indications and functions. Both of them have their own merits and are good drugs.

In 2000, 188 clinical trials were carried out with the approval of the State Food and drug administration; In 2001, 2149 phase IV clinical trials were conducted with the approval of the State Food and drug administration to further observe the adverse reactions and evaluate their safety. According to the judgment of the research doctors, there were 21 cases of adverse events related or possibly related to the research drug, and the incidence rate was 0.98%. The adverse events were gastrointestinal reactions, elevated transaminase, stomachache, chest tightness, decreased WBC, dry mouth, decreased RBC, and increased urinary RBC. The degree of adverse events was mostly mild, and a few were moderate. Nine cases were treated symptomatically and basically relieved. The adverse events related to the study drug and their incidence were gastrointestinal 6.51 times per thousand people, stomachache 1.40 times per thousand people, chest tightness 0.93 times per thousand people, transaminase elevation 0.47 times per thousand people, dry mouth 0.47 times per thousand people. In the trial, there were no rare adverse events.

matters needing attention

We know that the incidence rate of the disease has been increasing year by year and the age is becoming younger and younger. However, early treatment can cure the disease. Caution: 1. Patients with abnormal liver function should use it carefully and check liver function regularly. 2. There is no clinical data of pregnant or lactating women. 30 days is a course of treatment. There is no long-term clinical data.