Targeted drugs for liver cancer

summary

My mother suffered from liver cancer a few years ago. After surgery, she is much better and almost recovered. Let me talk about targeted drugs for liver cancer.

Targeted drugs for liver cancer

Drug 1: the mechanism of action of DDP is similar to that of cauterizer, which causes DNA cross linking and interferes with normal cell division. DDP has a wide anti-tumor spectrum and strong anti-cancer effect, and has good curative effect on many kinds of tumors. DDP is one of the commonly used chemotherapeutic drugs for liver cancer. Some scholars have compared the chemoembolization effect of DDP with that of MMC, and found that the effect of DDP was significantly better than that of MMC. In addition, DDP has a biochemical regulation effect on 5-FU (fluorouracil), and the combination of DDP and 5-FU has a synergistic effect. In recent years, some scholars have used DDP combined with 5-FU intrahepatic arterial continuous perfusion in the treatment of recurrent liver cancer, liver cancer with portal vein tumor thrombus, and liver cancer with ineffective embolization treatment, and achieved considerable results.

ADM is one of the most effective drugs in the treatment of liver cancer. ADM has the most serious cardiotoxicity in chemotherapy drugs, which can cause premature beat, 5t-t change, delayed myocardial damage, and even irreversible heart failure. The life-long cumulative dose of ADM should be controlled within 500-550mg / m2, generally without serious heart damage. The total amount of ADM should be less than 450 mg / m2 for patients over 70 years old, with previous heart disease, with high dose CTX and with mediastinal radiotherapy.

Drug 3: MMC has been widely used in various digestive tract tumors, especially in Japan. In recent years, it has been found that the effect of MMC in the treatment of gastrointestinal tumors is not good, and it may cause serious side effects (such as delayed myelosuppression, kidney damage, microangiopathy hemolytic anemia). MMC has been less used in the chemotherapy of gastrointestinal tumors, but it is still commonly used in interventional chemotherapy and chemoembolization of liver cancer.

matters needing attention

Dairy products and milk contain elements such as calcium and vitamin D, which can be combined with carcinogens in the intestine to remove harmful substances, so they have preventive effect on liver cancer; yogurt contains lactic acid bacteria, which can inhibit and kill spoilage bacteria in the intestine, reduce toxic substances in the intestine, and inhibit the growth of liver cancer cells. Therefore, drinking yogurt plays a very important role in the prevention and control of liver cancer.