How long can mucopolysaccharide syndrome live?

summary

The disorder of proteoglycan catabolism caused by congenital defects of proteoglycan degrading enzymes will lead to various types of mucopolysaccharide deposition. According to the different types of symptoms, the doctor will choose the appropriate examination method to make a definite diagnosis. Let me share with you the knowledge of inspection.

How long can mucopolysaccharide syndrome live?

The most reliable method for prenatal diagnosis of mucopolysaccharidosis is the detection of cultured amniotic fluid cells, but the experiment is demanding and difficult to carry out in general laboratory. Two simple and practical methods are toluidine blue qualitative method and uronic acid semi quantitative method. Here is a brief introduction.

Toluidine blue qualitative method is the same as urine mucopolysaccharide test. If the amniotic fluid is normal in the first trimester of pregnancy, it can be positive, but it is negative in the second trimester of pregnancy. If the amniotic fluid is positive, it indicates that the fetus has mucopolysaccharidosis.

Semiquantitative determination of glucuronic acid: acid mucopolysaccharide in amniotic fluid reacts with sodium tetraborate sulfuric acid solution to produce glucuronic acid, and the amount of acid mucopolysaccharide is reflected by the amount of glucuronic acid in each creatinine. With the progress of pregnancy, the content of glucuronic acid decreased gradually. The reference value of 16-20 weeks of pregnancy was 3.3-7.0 mg / Mg cr. if it was higher than this value, mucopolysaccharide deposition should be considered. In addition to morguio syndrome, this method has diagnostic significance for other types of mucopolysaccharidosis.

matters needing attention

In the diet must also control the salt intake, do not eat spicy food such as coffee, strong tea, you can eat more cereals such as cereals, oats or soybeans, you can drink more water or milk, but do not drink carbonated drinks.