What medicine does meningitis take good?

summary

Meningitis this kind of disease is the comparison of fear, in the hospital internship time, I saw some patients died of meningitis. Meningitis is divided into bacterial meningitis, tuberculous meningitis, viral meningitis, cryptococcal meningitis and so on. What medicine does meningitis take? Next, I'd like to share my views with you.

What medicine does meningitis take good?

Pyrazinamide. It can kill Mycobacterium tuberculosis in phagocytes growing slowly in acidic environment, but has little effect on Mycobacterium tuberculosis in neutral and alkaline environment. Pyrazinamide infiltrates into phagocytes and then enters into Mycobacterium tuberculosis. The amidase in the phagocyte makes it remove canthus amino group and transform it into pyrazine acid, which plays a bactericidal role. Pyrazinamide is an important antituberculous drug in the treatment of tuberculous meningitis. The main adverse reactions were liver damage, joint pain, swelling, ankylosis, limited activity and increased uric acid.

Streptomycin. It is a kind of aminoglycoside antibiotic, which can only kill Mycobacterium tuberculosis outside phagocytes, and it is a semi effective bactericide. It can inhibit the formation of 70s complex, peptide chain elongation and protein synthesis by interfering with the binding of aminoacyl tRNA with nucleosome 30S subunit, resulting in bacterial death. Streptomycin can penetrate part of the inflammatory m-brain barrier and is one of the important drugs for the early treatment of tuberculous meningitis. The main adverse reactions were ototoxicity and nephrotoxicity.

Isoniazid. Isoniazid can inhibit the DNA synthesis of Mycobacterium tuberculosis, destroy the enzyme activity in the cell, and kill both intracellular and extracellular Mycobacterium tuberculosis. No matter whether meninges have inflammation or not, they can permeate into cerebrospinal fluid rapidly. It is easy to produce drug resistance when used alone. The main adverse reactions were peripheral neuritis and liver damage.

matters needing attention

Meningitis patients must go to the hospital to do a comprehensive examination, develop their own treatment plan, actively cooperate with the doctor's treatment, pay attention to their living habits and eating habits, and maintain an optimistic attitude.