Symptoms of allergy

summary

Allergy is also called hypersensitivity. It means that the immune system is too sensitive to some substances that are not harmful to the body, such as pollen, animal fur, and so on, resulting in immune response, causing damage to the body. People's daily skin allergy, itchy skin, swelling, is an allergic reaction. Symptoms of allergy? Let's talk about it

Symptoms of allergy

Immediate type I allergy, also known as anaphylaxis, is the most common clinical reaction. It is characterized by IgE mediated, mast cells, basophils and other effector cells participate in the reaction by releasing bioactive mediators; The occurrence is fast and the extinction is fast; It is often manifested as physiological dysfunction without serious tissue damage; There are obvious individual differences and genetic tendency.

Different from the above three types of allergic reactions mediated by specific antibodies, type IV is mediated by specific sensitizing effector T cells. In this type of reaction, the local inflammation changes slowly, and the peak reaction occurs 24-48 hours after contacting with antigen, so it is called delayed type allergy. After the first contact with antigen, T cells transform into sensitized lymphocytes, making the body in an allergic state. When the same antigen enters again, the sensitized T cells recognize the antigen, differentiate and proliferate, release many lymphokines, attract and aggregate, and form an inflammatory reaction dominated by monocyte infiltration, and even cause tissue necrosis. The common type IV allergic reactions include contact dermatitis, transplant rejection, type IV allergic reactions in the process of infection with various bacteria and viruses (such as Mycobacterium tuberculosis and measles virus).

That is immune complex type (type III allergy), also known as vasculitis type hypersensitivity. Its main characteristics are: the free antigen combines with the corresponding antibody to form immune complex (IC). IF IC can not be cleared in time, it can deposit locally, activate complement, and trigger a series of chain reactions with the participation of platelets, neutrophils and other cells to cause tissue damage.

matters needing attention

1. Quit smoking and drinking; 2. Exercise, improve their own resistance; 3. Keep a good mood; 4. Identify allergens and keep away from allergens;