Diagnosis, treatment and follow-up of neurosyphilis

summary

My son has been diagnosed with congenital syphilis for more than three months. Now the test report is positive for RPR with a titer of 1. In order to prevent this situation, I'd like to introduce the diagnosis, treatment and follow-up of neurosyphilis.

Diagnosis, treatment and follow-up of neurosyphilis

Drug 1: the commonly used drugs are tetracycline, erythromycin, chloramphenicol, cephalosporin and penicillin. After suffering from syphilis, we still need to combine our own economic ability and symptoms to determine the choice of drugs.

Drug 2: benzathine penicillin G, 2.4 million U, after a single intramuscular injection, the blood concentration reached 0.34 μ g / ml, 0.09 μ g / ml and 0.03 μ g / ml on the 2nd, 6th and 13th day, respectively.

Drug 3: procaine penicillin. After intramuscular injection of 50000 U / kg, the blood concentration was 12 μ g / ml after 12 hours and 2.6 μ g / ml after 24 hours.

matters needing attention

Usually, the systemic symptoms like influenza may appear first, followed by swelling of lymph nodes and various damages of skin and mucous membrane. The symptoms of male syphilis are skin lesions with macular rash, macular papule and purulent herpes; mucosal lesions with syphilitic pharyngitis, mucosal plaque, syphilitic alopecia and other symptoms; some patients will have hoarseness, or even completely unable to pronounce. 90% of patients will have syphilis, which is the basic feature of secondary syphilis. When suffering from syphilis, because there is no obvious pain, it is often ignored by patients. Clinically, if you see a rash that is widely distributed, symmetrical, and with mild symptoms, you should ask for a detailed history to avoid missed diagnosis. This is one of the symptoms of male syphilis.