How does fatty liver show network to return a responsibility?

summary

The accumulation of triglycerides (neutral fat) in the cytoplasm is called steatosis. Under normal circumstances, except for adipocytes, there are few lipid droplets or only a few lipid droplets in general cells. If there are more lipid droplets in these cells, it is called steatosis. The composition of lipid droplets is mostly neutral fat, but it can also be phospholipid and cholesterol. Under electron microscope, the cytoplasmic fat of the cells appeared as adiposomes, and then fused into lipid droplets. How does fatty liver show network to return a responsibility? Let's talk about it.

How does fatty liver show network to return a responsibility?

1) Hepatic steatosis: one or more links in the process of fatty acid metabolism of hepatocytes are abnormal due to various factors, which can lead to steatosis. Visible to the naked eye, the liver is enlarged, the edge is blunt, the color is light yellow, soft, and the section is greasy. Microscopically, the nuclei of hepatocytes with severe steatosis are pressed to one side by the fat accumulated in the cytoplasm, which looks like adipocytes and can fuse into lipid sacs of different sizes. The distribution of steatosis in the hepatic lobule is related to its etiology. For example, when the liver congestion occurs, the hypoxia in the central area of the lobule is the most serious, so steatosis first occurs here. After long-term congestion, most cells in the central area of the lobule atrophy, degeneration or disappear, so the cells in the peripheral area of the lobule also suffer from hypoxia and steatosis. The fatty degeneration of hepatocytes mainly occurred in the area around the hepatic lobule. Steatosis of hepatocytes usually does not cause liver dysfunction. Severe steatosis of hepatocytes may lead to necrosis and secondary cirrhosis.

2) Myocardial steatosis: the subendocardial and papillary muscles of the left ventricle are most often involved. On the naked eye, it appears as roughly horizontal yellow stripes, alternating with dark red myocardium without fat change, which looks like tiger skin stripes, which is called Tiger spot heart. Microscopically: the myocardium can also contain a small amount of lipid droplets under normal conditions, but the number of lipid droplets increases obviously in the case of steatosis, and the fat vacuoles are mostly small and arranged in beaded shape, mainly located near the Z-band of muscle fibers and the distribution area of mitochondria, which is often the result of anemia and poisoning. Usually the function of the heart muscle is not affected. Significant myocardial degeneration is rare nowadays, which should be distinguished from myocardial fat infiltration.

3) Renal steatosis: severe anemia, poisoning or hypoxia, or increased glomerular capillary permeability, renal tubular epithelial cells, especially proximal convoluted tubules, can absorb the leakage of lipoprotein and cause steatosis. At first, lipid droplets were found in the basal part. Macroscopic view: the kidney is slightly enlarged, cortical thickening can be seen on the section, slightly yellowish.

matters needing attention

1、 We must stop drinking and eat more vegetables and fruits. 2、 Control energy intake: for patients with fatty liver, the energy supply should not be too high. In order to prevent weight gain and fat accumulation, patients with fatty liver who are engaged in mild activities and whose weight is within the normal range should be given 126-147 kJ (30-35 kcal) per kilogram per day. For those who are obese or overweight, it should be 84-105 kJ (20-25 kcal) per kilogram per day in order to control or reduce weight and strive to achieve the ideal or appropriate weight. Reasonable diet to prevent fatty liver, eat some coarse grains, do not eat sweet[ 1] Third, in diet collocation, we can match liver protection diet through food color. Three meals a day must be reasonably prepared to achieve the balance of coarse and fine nutrition, enough protein can remove liver fat. 4、 Careful use of drugs liver is the chemical factory of human body, any drug into the body must go through the liver detoxification. So don't take medicine every now and then. For patients with symptomatic fatty liver, we should be more careful in the selection of drugs to guard against the side effects of drugs, especially the drugs that damage the liver must not be used to avoid further aggravating the liver damage.