Central diabetes insipidus symptoms?

summary

Diabetes insipidus occurs when the urine volume exceeds 3L / d. The common disease causing diabetes insipidus is called diabetes insipidus, which can be summarized as hypothalamic pituitary diabetes insipidus (also known as central diabetes insipidus) caused by the deficiency or absence of hypothalamic pituitary antidiuretic hormone, and renal diabetes insipidus caused by the insensitivity of distal convoluted tubules and collecting tubules to antidiuretic hormone. Let's share my experience with you.

Central diabetes insipidus symptoms?

Diabetes insipidus can occur at any age, but most of them are young adults. The incidence rate of men and women is similar. Most of the onset of slow, often progressive, within a few days the disease can gradually obvious. A few of them can be sudden, and the onset date is exact.

The prominent clinical symptoms were polydipsia, polydipsia and polyuria. Polyuria is manifested in the increase of micturition frequency and urine volume. 24-hour urine volume can reach 5-10l or more. Urine does not contain sugar and protein. The urine specific gravity is usually 1.001-1.005, and the corresponding urine osmolality is 50-200 mOsm / L, which is significantly lower than that of plasma osmolality (290-310 mOsm / L). If the water intake is limited, the specific gravity of urine can be increased to 1.010, and the osmotic pressure of urine can be increased to 300 mOsm / L. If severe dehydration, glomerular filtration rate decreased significantly, then the specific gravity of urine can reach more than 1.010. Polyuria causes polydipsia and polydipsia. The amount of drinking water can reach 10L or more in 24h; Most patients like to drink cold drinks and cold water.

If there is enough water intake, the patient's daily life is similar to that of normal people, and may have mild dehydration symptoms, reduced saliva and sweat, dry mouth, loss of appetite, constipation, dry skin, poor sleep, memory loss, polyuria and polydipsia make the patient unable to sleep, affect rest, as time goes by, affect work, mental symptoms, headache, insomnia and depression.

matters needing attention

Avoid eating high protein, high fat, spicy and salty food, tobacco and alcohol. Because these can make plasma osmotic pressure rise, thus excited brain thirsty center; And easy to help fire heat, dry injury Yin, aggravating the disease symptoms such as thirst.