What is the cause of myelofibrosis

summary

Bone marrow fibrosis is a stubborn disease, which is difficult to cure in treatment and will recur repeatedly. Bone marrow fibrosis is a common chronic disease. In addition to genetic factors, it is caused by other types of diseases. The causes of the disease are complex and the treatment is troublesome. If not treated in time, it will seriously affect the hematopoietic function. Today, let me share what causes bone marrow fibrosis, hoping to help you.

What is the cause of myelofibrosis

First: the patient in the early stage due to blood cell proliferation, caused by mild bone marrow fibrosis and bone marrow cells showed varying degrees of proliferation, and megakaryocyte proliferation.

Second: in the middle stage, the patient's bone marrow was atrophic, fibrous tissue hyperplasia was prominent in the fibrosis stage, accounting for 40% - 60% of the bone marrow, hematopoietic cells accounted for 30%, megakaryocytes still proliferated, and bone trabeculae increased and thickened.

Third, in patients with advanced myelofibrosis, bone or trabecular hyperplasia is the main type, accounting for 30% - 40% of the bone marrow. There are obvious hyperplasia of fiber and bone tissue. Besides megakaryocytes, other hematopoietic cells are significantly reduced.

matters needing attention

Usually to avoid excessive fatigue, more to ensure adequate sleep. Keep a good mood and avoid being too nervous and depressed. But also to strengthen physical exercise, enhance the body's resistance.