What symptom does myasthenia have

summary

I think you all have a certain understanding of myasthenia, which is also one of the most distressing diseases. Myasthenia syndrome, also known as myasthenia syndrome, is an autoimmune disease involving the presynaptic membrane of neuromuscular junction. Pathogenic autoantibodies directly inhibit presynaptic pressure-gated calcium channels of nerve endings, leading to lems myasthenia. So what are the symptoms of myasthenia syndrome? Let's share with you.

What symptom does myasthenia have

First: myasthenia syndrome is mostly male patients, and most of them are 50-70 years old. More than half of them are accompanied by cancer, such as small cell lung cancer, gastric cancer, prostate cancer and rectal cancer, and occasionally accompanied by other autoimmune diseases, such as systemic lupus erythematosus.

Second, the symptoms of patients with myasthenia syndrome are mainly myasthenia and fatigue, but the distribution of affected muscles is different from myasthenia gravis. The skeletal muscles of the extremities are the main symptoms, and the symptoms of the lower limbs end up in the upper limbs, often combined with the disappearance of knee and ankle reflexes. The symptoms of the pelvic band and trunk muscles of the lower limbs are particularly obvious, and the muscles innervated by the brain, such as extraocular muscles and throat machines, are less affected. The muscle weakness of the affected muscle increased after a short period of forced contraction, but it became sick after continuous contraction.

Third: myasthenia syndrome patients generally have dry mouth, myalgia symptoms, some patients have impotence, constipation, less sweat, saliva and tears reduce autonomic nervous symptoms. Diagnosis of myasthenia syndrome in middle-aged and elderly male patients with lung cancer, myasthenia and fatigue symptoms, check the affected muscle after a short period of forced contraction, muscle strength but increased, after continuous contraction into morbid fatigue, telongxi and neostigmine test unknown stem, high-frequency nerve repetitive electrical stimulation showed specific response, serum acetylcholine antibody negative, usually can be diagnosed, the disease should be myasthenia gravis Force phase identification.

matters needing attention

Myasthenia in clinical will appear blepharoptosis, diplopia, strabismus, facial muscle and masticatory muscle weakness, but also cause apathy, can't blow and other performance.