What medicine does primary ovarian choriocarcinoma take good?

summary

Primary ovarian choriocarcinoma is a highly malignant ovarian tumor, which can be divided into pregnancy and non pregnancy choriocarcinoma. Choriocarcinoma gravidarum is not associated with other malignant germ cell tumors. What medicine does primary ovarian choriocarcinoma take good? Let's talk about it

What medicine does primary ovarian choriocarcinoma take good?

Chemotherapy regimens can be single drug or combined chemotherapy, and most of them are combined chemotherapy at present. Among the 6 cases reported by axe, 4 cases were treated with postoperative chemotherapy, 2 cases were treated with surgery alone without chemotherapy, 2 cases were treated with methotrexate (MTX) single chemotherapy, 2 cases were treated with combined chemotherapy: Methotrexate (MTX), vinblastine sulfate (VLB), actinomycin D (KSM, actinomycin D), bleomycin (ble), cisplatin (DDP), cyclophosphamide (CTX, Cytoxan).

Like other malignant germ cell tumors, primary ovarian choriocarcinoma should also be treated with surgery and chemotherapy. In recent years, the curative effect of PVB (vincristine, bleomycin, cisplatin) and other combined chemotherapy programs is obvious, and the prognosis of ovarian choriocarcinoma has also undergone fundamental changes. Therefore, in most cases, fertility preserving surgery can be used for unmarried patients without metastasis, such as uterus and contralateral ovary, The affected appendages and lesions were removed, and the greater omentum and retroperitoneal lymph nodes were removed.

Attention should be paid to toxicity during application. Fever could be induced by Pingyangmycin, which reached the peak after 2-3 hours and then decreased to normal. If the body temperature exceeds 39 ℃, take 1 tablet of indomethacin (indomethacin) orally and pay attention to rehydration. We should pay attention to interstitial pneumonia and pulmonary fibrosis, and regularly check lung function during chemotherapy. In the application of cisplatin (DDP), the urine volume should be more than 100ml / h, and a large amount of hydration should be given before DDP to reduce nephrotoxicity.

matters needing attention

Women in peacetime must also pay attention to a reasonable diet, especially in the menstrual period, need to pay more attention to diet and health, if not pay attention to health, it may cause some other gynecological diseases.