Symptoms of h7n9 infection

summary

Recently, avian influenza h7h9 has made a comeback, which makes Chinese people talk about chicken color change. In the face of its high mortality, the incubation period of human infection with h7n9 avian influenza is generally within 7 days. Patients usually present with influenza like symptoms, such as fever, cough, less sputum, headache, muscle soreness and general discomfort. Severe patients developed rapidly, manifested as severe pneumonia. Most of them had body temperature above 39, dyspnea and hemoptysis; Acute respiratory distress syndrome, mediastinal emphysema, sepsis, shock, disturbance of consciousness and acute kidney injury can be rapidly developed. How to identify early in order to improve the survival rate? Tell us about the symptoms of h7n9 infection.

Symptoms of h7n9 infection

1、 General manifestations: patients usually present with influenza like symptoms, such as fever, cough, less sputum, headache, muscle soreness and general discomfort. Severe patients developed rapidly, manifested as severe pneumonia, body temperature mostly continued above 39 ℃, dyspnea, hemoptysis and sputum; Acute respiratory distress syndrome, mediastinal emphysema, sepsis, shock, disturbance of consciousness and acute kidney injury can be rapidly developed.

2、 Laboratory examination 1. Blood routine. The total number of white blood cells is generally not high or low. Most of the severe patients had leukopenia, lymphopenia and thrombocytopenia. 2. Blood biochemical examination. In most cases, creatine kinase, lactate dehydrogenase, aspartate aminotransferase, alanine aminotransferase, C-reactive protein and myoglobin were increased. 3. Pathogen detection（ 1) Nucleic acid detection. Real time PCR (or RT-PCR) was used to detect the nucleic acid of h7n9 avian influenza virus in respiratory tract samples (such as nasopharyngeal secretions, oral gargles, tracheal aspirates or respiratory epithelial cells)（ 2) Virus isolation. H7n9 avian influenza virus was isolated from respiratory tract specimens of patients.

3、 Patients with pneumonia on chest imaging showed patchy images in the lung. In severe patients, the lesions progressed rapidly, showing multiple ground glass opacity and pulmonary consolidation in both lungs, with a small amount of pleural effusion. When ARDS occurs, the lesions are widely distributed.

matters needing attention

The prognosis of severe patients infected with h7n9 avian influenza is poor. The prognostic factors may include age, underlying diseases and complications.