What is the cause of vitiligo

summary

There are many people suffering from vitiligo. Some time ago, there were white spots on my colleagues' skin. I didn't know it was vitiligo until I went to the hospital for examination. I've been wiping medicine for a long time. I'll tell you what causes vitiligo!

What is the cause of vitiligo

First, the theory of heredity. Vitiligo can appear in twins and families, indicating that heredity plays an important role in the pathogenesis of vitiligo. Studies have shown that vitiligo has incomplete penetrance and multiple pathogenic loci. The decrease of copper or ceruloplasmin levels in the blood and skin of patients with vitiligo leads to the decrease of tyrosinase activity, which affects the metabolism of melanin.

Second: vitiligo can be combined with autoimmune diseases, such as thyroid disease, diabetes, chronic adrenal insufficiency, pernicious anemia, rheumatoid arthritis, malignant melanoma and so on. The specific antibodies of various organs can also be detected in serum, such as anti thyroid antibody, anti gastric parietal cell antibody, anti adrenal antibody, anti parathyroid antibody, anti smooth muscle antibody, anti melanocyte antibody, etc.

Third: mental factors are closely related to the onset of vitiligo. Most patients have mental trauma, excessive tension, depression or depression at the onset or skin lesion development stage. The degeneration of nerve endings in leukoplakia also supports the neurochemical theory. Trauma, sun exposure and some photosensitive drugs can also induce vitiligo.

matters needing attention

Many people have misunderstandings or prejudices about people with vitiligo and think they look terrible. In fact, this is because we do not understand vitiligo. In fact, this disease has no effect on our communication with them, and will not hinder our normal social life.