Symptoms of endometrial cancer metastasis

summary

The growth of endometrial carcinoma is slow, and the time limited in the endometrium is long, but a few of them develop rapidly. The main routes of metastasis were direct spread, lymph node metastasis and hematogenous metastasis in late stage. In the late stage, the body's uncomfortable symptoms of endometrial cancer patients are getting worse and worse. Once patients with endometrial cancer have liver metastases, it is often not only vaginal bleeding symptoms of primary cancer. Let's talk about the symptoms of endometrial cancer metastasis.

Symptoms of endometrial cancer metastasis

1. At the beginning of direct spread, the cancer spread along the endometrium, up through the uterine horn to the fallopian tube, down to the cervical tube, and continued to spread to the vagina. It can also infiltrate into the serosa of uterus and extend to fallopian tube and ovary. It can be widely planted in pelvic peritoneum, recto uterine depression and omentum.

2. Lymph node metastasis is the main metastasis pathway of endometrial carcinoma. When the cancer infiltrates into the deep muscle layer, or spreads to the cervical canal, or the cancer tissue is poorly differentiated, it is easy to have lymph node metastasis. The metastasis pathway is related to the growth site of the tumor. The cancer in the fundus of uterus is located along the lymphatic network of the upper part of the broad ligament and through the pelvic infundibulum ligament to the ovary. Up to the para aortic lymph nodes. The cancer foci in the corner of uterus extend along the ligament teres to the inguinal lymph nodes. The lymph node metastasis pathway of the lower uterine segment and cervical canal is the same as that of cervical cancer, which can reach the parametrial, internal iliac, external iliac and common iliac lymph nodes. The tumor in the posterior wall of uterus can spread to the rectal lymph nodes along the uterosacral ligament. Endometrial cancer can also spread to the front of the uterus to the bladder, through retrograde drainage to the anterior vaginal wall.

3. Hematogenous metastasis is rare. In the late stage, it was transferred to lung, liver and bone by blood.

matters needing attention

The treatment of endometrial cancer should be based on the patient's age, physical condition, lesion range and histological type. Because the majority of endometrial carcinoma is adenocarcinoma, it is not sensitive to radiotherapy, so the treatment is mainly surgery, and other comprehensive treatments include radiotherapy, chemotherapy and drugs (chemotherapy, hormone, etc.). Early stage patients were mainly operated, and adjuvant therapy was selected according to the results of operation pathological staging and high risk factors of recurrence; The advanced patients were treated with surgery, radiotherapy and drugs.