Pre death symptoms of signet ring cell carcinoma of stomach?

summary

Signet ring cell carcinoma of stomach is one of the highly malignant tumors, accounting for 9.9% of gastric cancer. It has the characteristics of strong invasion, rapid progression and high degree of malignancy. Gastric cancer is divided into papillary adenocarcinoma, tubular adenocarcinoma, mucinous adenocarcinoma, signet ring cell carcinoma, adenosquamous carcinoma, squamous cell carcinoma and undifferentiated carcinoma. Among them, signet ring cell carcinoma is a special type of gastric cancer, which contains a lot of mucus. Because the cells are full of mucus, the nucleus is squeezed to one side of the cell, making it look like a ring, so it gets its name. Most experts believe that the occurrence of the disease may be related to the vigorous metabolism of estrogen in young women. Pre death symptoms of signet ring cell carcinoma of stomach? Let's talk about it.

Pre death symptoms of signet ring cell carcinoma of stomach?

In the early stage, most patients had no obvious symptoms, and a few had nausea, vomiting or upper gastrointestinal symptoms similar to ulcer disease. Pain and weight loss are the most common clinical symptoms in advanced patients.

Patients often have more clear upper gastrointestinal symptoms, such as abdominal discomfort, fullness after eating, with the progress of the disease, abdominal pain, loss of appetite, fatigue. According to the location of the tumor, there are also special manifestations.

Cancer of cardia and fundus of stomach may have retrosternal pain and progressive dysphagia; Patients with lesions near the pylorus had pylorus obstruction; After the tumor destroys the blood vessel, may have hematemesis, black stool and so on digestive tract hemorrhage symptom. Persistent abdominal pain often indicates tumor expansion beyond the gastric wall, such as supraclavicular lymphadenopathy, ascites, jaundice, abdominal mass, anterior rectal fossa and mass. Late stage patients often appear anemia, emaciation, malnutrition and even cachexia.

matters needing attention

(1) The principle of radical operation is to remove part or all of the stomach including the cancer and the gastric wall that may be infiltrated. According to the clinical staging standard, the lymph nodes around the stomach are removed and the digestive tract is reconstructed（ 2) Palliative surgery can not remove the primary focus, in order to reduce the symptoms caused by obstruction, perforation, bleeding and other complications, such as gastrojejunostomy, jejunostomy, perforation repair, palliative gastrectomy, etc.