Typical symptoms of adult sepsis?

summary

Now the biological clock in nature is a great threat to the human body. In fact, it is fungi. If our body encounters some bad conditions, most of them are caused by fungi. Sepsis is one of them, but I believe many people have only heard about this disease, but they don't know much about it. Now let's popularize the typical symptoms of adult sepsis?

Typical symptoms of adult sepsis?

① Fever is the most common and earliest symptom of the disease. Other manifestations, such as rash, joint muscle symptoms, peripheral blood leukocyte increase, may appear several weeks or even months after fever. More than 80% of the patients presented with typical diastolic fever. Their body temperature rose abruptly in the evening to above 39 ℃ with or without shivering. However, without antipyretic treatment, their body temperature could automatically return to normal in the morning of the next day. Usually, the peak temperature is once a day, and twice a day is rare.

② Rash is another major manifestation of the disease, which is seen in more than 85% of patients. The typical rash is orange red macular or macular papule. Sometimes the rash is variable in shape and can be urticaria like. The rash mainly distributed in the trunk, limbs, but also in the face. The characteristic of the rash is that it is often accompanied by fever. It often appears in the evening when the fever begins and disappears in the morning. Another skin abnormality is due to mechanical stimulation or hot water bath, such as folding clothes and bedding, rubbing and scratching, which makes the corresponding parts of the skin diffuse erythema and may be accompanied by mild pruritus. This phenomenon is Koebner phenomenon, which is seen in about 1 / 3 of the patients.

③ Joints and muscles - almost 100% of patients have joint pain, arthritis in more than 90%. The knee and wrist joints were most frequently involved, followed by ankle, shoulder and elbow joints. The proximal interphalangeal joint, metacarpophalangeal joint and distal interphalangeal joint were also involved. In the early stage of the disease, the number of joints involved is less, and in the future, it can increase and present polyarthritis. In many patients, the cartilage and bone tissue of the affected joint may be eroded and destroyed, so there may be joint stiffness and deformity in the late stage. Muscle pain is common, accounting for more than 80%. Most patients have different degrees of muscle soreness when they have fever, and some patients have muscle weakness and slight increase of muscle enzymes.

matters needing attention

Most patients have a good prognosis. One fifth of the patients had remission within one year and no recurrence later. One third of the patients had complete remission after repeated attacks for several times, and the recurrence time was uncertain, but the symptoms of recurrence were often lighter than that of initial onset, and the duration was shorter. The rest of the patients become chronic, mainly chronic arthritis, a few can develop to severe joint damage, and can lead to joint ankylosis, and even need joint replacement. Patients with polyarthritis (≥ 4 joints) or foot, shoulder and hip joint involvement are prone to chronic disease. In addition, children who need systemic hormone therapy for more than 2 years often have poor prognosis. The causes of death include acute liver failure, disseminated intravascular coagulation, secondary amyloidosis and sepsis.