What does urinary protein represent

summary

Last week, I went to the hospital for a physical examination. After I got the physical examination report, I found a trace of urinary protein. I don't know what's going on. I went to consult a professional doctor. The doctor gave a lot of suggestions according to my physical examination report. Now let me tell you what the trace of urinary protein represents.

What does urinary protein represent

First: from a scientific point of view, the normal urine protein in urine comes from plasma. Because the glomerular filtration membrane has a control device for protein, and the renal tubules have a selective reabsorption effect on protein, the macromolecular protein with larger molecular weight than albumin is limited. Although the protein with smaller molecular weight than albumin is easy to pass through, these low molecular proteins are mostly reabsorbed by the renal tubules. Therefore, albumin is the main protein from plasma in normal urine.

Second: urine protein is one of the symptoms of kidney disease, but the urine protein of chronic kidney disease, the patient's friends do not understand. Because in life of not pay attention, often ignore its harm. Experts remind patients that the biological changes of tubular cells caused by urinary protein are very serious. Many kidney diseases with urinary protein have excessive cell proliferation, which represents a kind of non adaptive response, and can lead to renal failure.

Third: the aggravation of tubulointerstitial hypoxia caused by proteinuria: the reabsorption of proteinuria requires extra energy to digest a large amount of protein, which can cause tubular cell hypoxia and cause tubular cell damage. More and more evidences show that proteins can directly regulate the function of tubular cells, change their growth characteristics and the phenotypic expression of cytokines and matrix proteins, which can lead to the release of PDGF, FN and MCP-1 from the basal side of tubular cells and induce fibrosis.

matters needing attention

Patients with microalbuminuria should pay attention to strengthen exercise, enhance immunity, reduce or prevent obesity. In addition, we should get rid of the bad habit of smoking and excessive drinking. Of course, it is better to keep a happy mood, so as to better treat the disease.