How to do after nephrectomy?

summary

Renal tumors account for 2% to 3% of the total malignant tumors in adults. Renal cell carcinoma (RCC) accounts for about 90% of renal malignancies. According to statistics, the incidence rate of RCC worldwide increased by 2% every year. It has risen to tenth in the 08 years from the thirteenth common malignant tumors. As a more complex disease, how to do after nephrectomy? How can it be?

How to do after nephrectomy?

First: after a large sample of renal cell carcinoma, the postoperative recurrence interval ranged from 3 months to 29 years, with an average interval of 17 to 44.5 months. The median recurrence interval was about 12~17 months. The factors influencing the recurrence of renal cell carcinoma include T stage of primary tumor, histological type of primary tumor, lymph node positive and margin positive at radical operation, tumor size, tumor nuclear grade, tumor necrosis and sarcomatosis.

Second, there is no unified model for the treatment of local recurrence of renal tumors. In the past, it was considered that the local recurrence of renal cell carcinoma after operation was mostly advanced, with poor prognosis and great trauma after reoperation. Therefore, surgery is rarely recommended for the treatment of local recurrence of renal cell carcinoma after operation. However, with the development of imaging, more and more sporadic local recurrences have been found, and the reports of surgical treatment have increased significantly. It was found that the 5-year survival rate was only 13% in conservative treatment group and 51% in surgical treatment group.

Third: to prevent recurrence after surgery, we must supplement the patients with trace element selenium: clinical use is combined with Hecun malt selenium capsules for cancer patients, selenium is known as the "king of cancer". In September 2003, the U.S. Food and Drug Administration (FDA) recognized selenium as an anti-cancer agent, which is the official medical statement of the U.S. government that selenium can inhibit cancer. Some scientists supplement selenium to cancer patients for a long time, which reduces the death rate of cancer patients by 50%. A large number of studies have shown that selenium is a powerful tumor inhibitor, which can inhibit the growth of cancer cells and block the energy supply of cancer cells. At present, many scholars believe that selenium is not only effective in cancer prevention, but also can be used as adjuvant of chemotherapy to reduce the side effects of chemotherapy drugs and increase drug tolerance.

matters needing attention

In conclusion, the treatment of local recurrence of renal cell carcinoma should be considered comprehensively. For occasional local recurrence, low-risk primary tumor and long recurrence interval, reoperation is feasible; Preoperative imaging data (such as the size of the recurrent tumor, the supply of blood vessels, the relationship with the surrounding organs, etc.) can provide reference for reoperation.