Why are people very thin after bone marrow transplantation

summary

Now there are more and more people with leukemia due to environmental reasons. The only way to treat leukemia is bone marrow transplantation. I'd like to explain to you the reasons why bone marrow transplant people are thin.

Why are people very thin after bone marrow transplantation

First, bone marrow transplantation, or hematopoietic stem cell transplantation, is a method of treating a series of diseases by intravenous infusion of hematopoietic stem and progenitor cells to reconstruct the normal hematopoietic and immune system of patients. Hematopoietic stem cell transplantation has replaced the term "bone marrow transplantation" to a certain extent, because hematopoietic stem cells not only come from bone marrow, but also can be mobilized into peripheral blood by hematopoietic factors, and can also come from umbilical cord blood. These hematopoietic stem cells can be used to reconstruct the hematopoietic and immune system.

Second, leukemia is a kind of hematopoietic stem cell malignant clonal disease. Clonal leukemia cells proliferate and accumulate in bone marrow and other hematopoietic tissues, infiltrate into other tissues and organs, and normal hematopoiesis is inhibited due to uncontrolled proliferation, dysfunction of differentiation and blocked apoptosis. Anemia, hemorrhage, infection, fever, swelling of liver, spleen, lymph nodes and bone pain were observed in different degrees. Now the incidence rate of leukemia in China is very high, and the number of patients is increasing sharply every year. We must pay attention to it.

Third, some people don't understand the method of bone marrow donation and are afraid of it. "In fact, bone marrow donation can be regarded as blood donation instead of" bone drilling and marrow extraction. " City Blood Donation Office staff said, now take in peripheral blood collection of hematopoietic stem cells, that is, after injection of mobilization agent, let a large number of bone marrow hematopoietic stem cells released into the blood, as long as the elbow vein collection, through a "blood cell separator" can separate and collect hematopoietic stem cells. Therefore, bone marrow transplantation has no effect on the health of donors.

matters needing attention

The reason for the failure of transplantation may be that the patient has received multiple blood transfusions, and the chemistry of hematopoiesis and immune cells. The radiation after my transplantation is not strong enough, and the bone marrow transfused is not enough. Drug damage to bone marrow and so on. After bone marrow transplantation, we must keep a good mood, eat some nutritious food, don't eat some junk food, and pay attention to the reasonable postoperative exercise.