Why are more and more newborns suffering from congenital heart disease

summary

Congenital heart disease (CHD) is one of the most common congenital malformation diseases, which is caused by abnormal development of heart and large blood vessels in fetus. The incidence rate of this disease is between 6% and 10% of the live babies. The incidence rate of dead babies is higher. It is estimated that there are about 150000 newborns suffering from the disease every year in China, and one third of them die within one year due to ineffective treatment. At present, surgical operation is the main treatment. Open heart surgery under the condition of cardiopulmonary bypass and deep hypothermia anesthesia greatly improves the effect of radical operation for congenital heart disease.

Why are more and more newborns suffering from congenital heart disease

First, the etiology of most congenital heart diseases is still unclear, but according to the investigation, it may be related to genetic, maternal and environmental factors. Genetic factors can be divided into single gene genetic deletion and polygene genetic deletion, among which polygene genetic deletion is the main one. Due to the lack of gene, the chromosome can not be translated, resulting in the corresponding organ or structure deformity.

Second: maternal factors are mainly maternal infection and maternal diseases, especially maternal early pregnancy with virus infection, such as influenza, mumps and so on. Some maternal metabolic diseases also cause fetal congenital heart disease, such as diabetes, hyperuricemia and so on. Some studies have shown that the use of drugs during pregnancy is also closely related to the incidence rate of the disease, so the use of drugs during pregnancy must be cautious.

Third: environmental factors are the key to the increase of the incidence rate of the disease. Research shows that 92% of the congenital heart disease causes environmental factors change rapidly. The damage of the environment is also aggravated. Haze, air dust, electronic radiation and environmental noise may be the factors that affect the disease. So I hope to give the fetus a good growth environment during pregnancy.

matters needing attention

It is generally believed that the fifth week to the eighth week of early pregnancy is the most critical period of fetal heart development in the mother. At this time, we should pay attention to the influence of various factors on fetal development. Infection with rubella virus during the first three months of pregnancy increases the risk of congenital heart disease. And the early onset of the disease may not have more obvious symptoms, but the disease will still aggravate the development, generally timely diagnosis and treatment, so as not to miss the opportunity for surgery.