What are the symptoms of renal transplant rejection?

summary

Renal transplantation rejection is a kind of immune reaction. Because the transplanted kidney has allogeneic antigen, the immune system of the recipients has cellular and humoral immune response to this allogeneic antigen, which is called rejection. What are the symptoms of renal transplant rejection? Let's talk about it.

What are the symptoms of renal transplant rejection?

Hyperacute rejection: it usually occurs within 48 hours after the graft is connected with the recipient's blood vessels, and the fastest occurs within a few minutes. At present, there is no effective treatment for hyperacute rejection. Once it appears, we have to resect the transplanted kidney and prepare for re transplantation. Hyperacute rejection is mainly prevention.

Accelerated rejection: occurred in 3-5 days after operation, manifested as obvious swelling, tenderness, fever, oliguria and hypertension, and increased serum creatinine and white blood cells. Accelerated rejection can be treated with methylprednisolone, ATG, OKT3 and plasma exchange.

Acute rejection: occurs one week after renal transplantation and can coexist with chronic rejection. The clinical manifestations are fever, decreased urine volume, hypertension, tenderness of transplanted kidney, and elevated serum creatinine. Now due to the application of cyclosporine A, the clinical manifestations are not typical, and only the changes of renal function may be found.

matters needing attention

At present, there is no exact and effective treatment for chronic rejection. Bailing capsule + Compound Danshen tablets, mycophenolate mofetil, anti hypertension, anticoagulation and Hypolipidemia may have a certain effect on delaying the progress of renal allograft dysfunction.