Non lipoid histiocytosis?

summary

Non lipoid histiocytosis, also known as letrell sever disease. Non lipoid histiocytosis is a kind of acute differentiated histiocytosis. The age of onset is young, and the lesions often invade multiple systems. However, eye and orbital involvement is rare. The prognosis of non lipoid histiocytosis is poor. The etiology of non lipoid histiocytosis is unclear, which may be related to immune dysfunction. Non lipoid histiocytosis? Let's talk about it

Non lipoid histiocytosis?

About 20% of the patients were asymptomatic and only found in chest X-ray examination. Most of the cases are slow, with low fever, fatigue, dry cough and dyspnea. 20% of the patients were complicated with diabetes insipidus, and the other 20% were complicated with single or multiple long bone granuloma. There was no eosinophilia in peripheral blood.

Some patients can relieve themselves. But often repeated onset, the final formation of pulmonary fibrosis, lung cysts. Spontaneous pneumothorax may occur if the cyst is ruptured. In severe cases, it can lead to respiratory and right heart failure. Chest X-ray showed diffuse small, unclear edge, spot shadow, and honeycomb lung due to a large number of fibrosis in the late stage.

Most of them are symmetrical polyarthritis, which can cause joint deformity and dysfunction. It often invades the limbs, spine and temporomandibular joints. The distal interphalangeal joint was the most affected. When the onset is insidious, the disease can develop into joint deformity asymptomatic, especially in hands and feet. Recurrent carpal tunnel syndrome and fibroproliferative hand contracture of metacarpal fascia are also common manifestations of the disease.

matters needing attention

We should increase the intake of protein and carbohydrate. Protein can be decomposed into amino acids in the body, which has a strong repair effect on tissue damage. Secondly, as the coenzyme of muscle tissue synthesis, B vitamins are also of great significance to the overall muscle repair. You can eat more fruits and vegetables containing vitamin B, such as wheat germ, soybean, peanut, black rice, germ rice, etc. The best protein is fish and beef.