Does bladder cancer need chemotherapy before operation

summary

My uncle felt extremely uncomfortable when he urinated some time ago. When he went to the hospital, he was found with bladder cancer. The doctor suggested surgery. I don't know whether chemotherapy is needed before surgery. Now let me tell you whether chemotherapy is needed before surgery for bladder cancer.

Does bladder cancer need chemotherapy before operation

First: No, bladder cancer is not sensitive to chemotherapy. There was no evidence of preoperative chemotherapy for bladder cancer. The tumor thrombus / nerve invasion indicated by postoperative pathology is a high-risk factor with poor prognosis, which has nothing to do with cancer cell proliferation. Postoperative adjuvant chemotherapy should be performed according to high risk factors.

Second: preoperative chemotherapy, also known as neoadjuvant chemotherapy, combined with surgery in the treatment of locally advanced bladder tumor patients, is safer. Compared with simple cystectomy, it can reduce the residual tumor in bladder resection specimens and improve the prognosis. Neoadjuvant chemotherapy combined with four drugs can be used in patients with locally advanced bladder cancer who will undergo radical cystectomy, but attention should be paid to: select patients with good renal function, closely monitor the toxic and side effects of chemotherapy, and timely intervene in case of serious side effects.

Third: even in the United States, where medical treatment is developed, neoadjuvant chemotherapy is applied to less than 2% of patients with muscle invasive bladder cancer. Expert analysis has the following misunderstanding factors, hindering the wide application of neoadjuvant chemotherapy before bladder cancer surgery, interventional Chinese medicine treatment, can play a short-term role in reducing toxicity and increasing efficiency.

matters needing attention

In principle, bladder cancer does not need chemotherapy before operation, but due to the differences of patients' physique and condition, different patients can choose whether to carry out chemotherapy under the advice of doctors, which is more conducive to their own treatment.