How long does purulent meningitis coma last?

summary

Purulent meningitis is most common in children, often in winter and spring season, the disease is infectious, so it is easy to form an epidemic trend, the main way of transmission is the spread of droplets, often from the respiratory tract into the human body, a large number of reproduction in the respiratory tract, in the human body resistance down, into the blood, thus into the meninges, resulting in purulent meningitis. So, in life, we should pay attention to it, the following specific talk about purulent meningitis coma how long?.

How long does purulent meningitis coma last?

First: purulent meningitis is one of the serious intracranial infections, often coexisting with purulent encephalitis or brain abscess. The most common pathogens of purulent meningitis were diplococcus meningitidis, Diplococcus pneumoniae and Haemophilus influenzae type B, followed by Staphylococcus aureus, Streptococcus, Escherichia coli, proteus, anaerobic bacteria, Salmonella, Pseudomonas aeruginosa (Pseudomonas aeruginosa), etc. Meningococcal infection is most common in children, but also in adults. Influenza meningitis mainly occurs in children under 6 years old. Pneumococcal meningitis often occurs in the elderly and infants. Escherichia coli is the most common pathogen of neonatal meningitis. Staphylococcus aureus and Pseudomonas aeruginosa meningitis are often secondary to lumbar puncture and neurosurgery.

Second: 90% of the cases. Acute onset, symptoms of upper respiratory tract infection, such as sore throat, runny nose, high fever, chills and shivering after entering the stage of septicemia. In 70% of the cases, dark or purplish red ecchymosis and ecchymosis were found. One to two days later, the patient entered the meningitis stage and developed intracranial hypertension, characterized by increased headache, frequent vomiting (jet like) and meningeal irritation (i.e. stiff neck, positive angle arch reflexes and Brucella sign), elevated blood pressure, fear of light, mania and even respiratory failure. Body pain, restlessness and dull expression and other manifestations of toxemia, severe delirium, coma. Infants (under 2 years old) often have atypical meningitis symptoms, such as high fever, vomiting, refeeding, crying and even convulsion, due to the skull suture and fontanel patent. Although there is no meningeal irritation sign, the full anterior fontanel is helpful for the diagnosis.

Third: this type is more common in children, the condition is ferocious, if not timely rescue can be within 24 hours of death. Often high fever, headache, vomiting, severe mental depression, disturbance of consciousness, convulsion, oliguria or anuria, brain parenchymal damage, patients quickly into coma, frequent convulsions, hemiplegia, high blood pressure, one side pupil dilation, disappearance of light reflex, eyeball fixation, soon respiratory failure and death. This type can be divided into fulminant shock type and fulminant encephalitis type. In addition to the common symptoms, the prominent manifestations of tike type are systemic poisoning, extreme mental malaise, pale complexion, cold limbs, skin pattern, decreased urine volume, decreased blood pressure, more clear cerebrospinal fluid, slightly increased or normal cell number. Blood culture and ecchymosis smear were positive. Fulminant encephalitis is characterized by severe headache, restlessness, frequent vomiting, convulsions, rapid coma, and eventually cerebral hernia and respiratory failure. The patients with both shock and encephalitis were mixed type, and the mortality was very high.

matters needing attention

The patients and carriers are the source of infection of the disease. Vaccination can effectively prevent the occurrence of the disease. The prognosis of the disease is closely related to the time when the pathogenic bacteria are found and whether the timely antibacterial treatment is carried out. In the diagnosis of the disease, should be carried out as soon as possible enough drug sterilization treatment. Because the lesion is in the meninges, the effective concentration of drugs in cerebrospinal fluid is needed for treatment, so the drugs that can pass through the blood-brain barrier should be selected.