How does rubella IgM calculate negative?

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For the examination of rubella, rubella virus antibody is an important indicator to test whether you have rubella, so learning to read the report can also achieve the bottom of the heart. Now I'll put the rubella IgM how to calculate negative? Let me tell you this.

How does rubella IgM calculate negative?

First: rubella virus is an RNA virus, belonging to the family of enveloping viruses, which is a virus limited to human beings. The antigenic structure of rubella virus is quite stable, and there is only one antigenic type. Antibody refers to the immunoglobulin produced by plasma cells derived from B lymphocytes or memory cells, which can specifically bind to the corresponding antigen.

Second, the positive rate of rubella virus antibody increases with age, and newborns can obtain rubella virus IgG antibody through their mothers infected with rubella virus in early years. IgM antibody was produced about 4 days after eruption, peaked in about 10 days, lasted for 6-12 weeks, and occasionally lasted for one year; IgG antibody appeared a little later than IgM antibody, gradually increased, reached the peak in 1-2 months, and then decreased. More than 80% of the people were positive for IgG antibody.

Third, both IgG and IgM antibodies of rubella virus are positive, or the titer of IgG antibody is greater than or equal to 1:512, indicating the recent infection of rubella virus. The IgG and IgM antibodies of rubella virus were negative, indicating that they had not been infected by rubella virus. The IgG antibody titer of rubella virus was less than 1:512, and IgM antibody was negative, indicating that there was a history of previous infection.

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Rubella virus antibody IgM negative and positive significance are different, or need specific situation specific analysis, I hope the above introduction to help you.