How to differentiate congenital eyelid defect?

summary

Congenital eyelid defect is a rare congenital anomaly. The animal experiment showed that the second generation of embryo could have eyelid defect, congenital cataract and microphthalmos after X-ray irradiation and injection of choline or naphthalene. Some patients' families have blood marriage history. There are reports of mother, daughter or brother suffering from the disease at the same time. How to differentiate congenital eyelid defect?

How to differentiate congenital eyelid defect?

Most of the typical congenital eyelid defects are triangular in shape, with the base facing the eyelid margin or quadrilateral in shape. The upper eyelid defects were mostly located in the middle 1 / 3 or the inner 1 / 3, and the lower eyelid defects were mostly located in the outer 1 / 3. The size of the defect can vary, generally including the skin, meibomian, conjunctiva and other full-thickness defects, so the edge of the defect is smooth, no eyelashes, no sweat glands, no scar tissue. Conjunctiva and skin were still preserved in a few patients, only a part of meibomian plate was missing.

This disease can also be accompanied by congenital abnormalities of the eye and other parts of the body, such as persistent pupillary membrane, pupil heterotopia, iris, choroidal defect, symblepharon, microphthalmos, cleft palate, cleft lip, facial cleft, abdominal hernia, but rare. If the defect occurs on the lateral side of the lower eyelid, it is often accompanied by zygomatic dysplasia on the same side.

Symptoms and signs, mostly monocular, occurred in the upper eyelid are more common. Most of the defects were located on the medial side of the center. Most of the defects are triangular in shape, and the base is located at the palpebral margin. But there are also trapezoid or oval. If the defect is large, the cornea may lose its protection and become dry or infected.

matters needing attention

The cause of the disease is a rare congenital anomaly. Pathophysiology is a rare congenital abnormality. Diagnostic examination. Diagnosis can be made according to clinical manifestations. Treatment plan. Hand repair to protect cornea or improve face.