What is the cause of abdominal aorta coarctation?

summary

Coarctation of aorta is a common congenital cardiovascular malformation with an incidence of 0.2-0.6 per 1000 live births. It ranks the eighth in the common congenital heart diseases, accounting for 5% - 8% of all congenital heart diseases. Male is more than female. What is the cause of abdominal aorta coarctation? Let's talk about it

What is the cause of abdominal aorta coarctation?

Abdominal aortic coarctation is first associated with syphilis and other infectious diseases. In 1937, maycock first proposed that abdominal aortic stenosis might be a congenital disease. He believed that abdominal aortic stenosis was caused by the absence or incomplete fusion of the dorsal aorta at the fourth week of pregnancy.

According to doeer, abdominal aortic stenosis is caused by occlusion of the fourth right parotid arch artery entrance. From the morphogenetic point of view, that is, excessive formation of vascular wall, resulting in vascular stenosis.

Some people put forward the congenital Theory: it is said that two dorsal arteries are absent with one of the two original tubes closed; it is said that two fetal dorsal aortas are over fused; it is said that viruses such as rubella cause mitosis inhibition of vascular wall smooth muscle cells, resulting in early fetal or infant aortic development arrest.

matters needing attention

It is necessary to carry out prenatal genetic or chromosomal examination to prevent the disease. Once aortic coarctation is diagnosed, surgical treatment should be performed regardless of symptoms.