Analgin poisoning symptoms?

summary

Analgin is a compound of aminopyrine and sodium sulfite. It is soluble in water and has faster and stronger antipyretic and analgesic effects than aminopyrine. In general, it is not the first choice of medicine, only in the case of acute high fever, severe illness, and no other effective antipyretic drugs available. Analgin poisoning symptoms? Let's talk about it

Analgin poisoning symptoms?

1. Hematology: can cause agranulocytosis, the incidence rate is about 1.1%, showing acute onset, severe fatal risk. It can also cause immune hemolytic anemia, thrombocytopenic purpura and aplastic anemia When intramuscular injection, some patients may have sweating, chest tightness, sudden drop of blood pressure, resulting in collapse.

2. Skin: it can cause urticaria, drug eruption, exudative erythema and other allergic manifestations. Severe cases can occur exfoliative dermatitis and epidermolysis bullosa, and even lead to death. Anaphylactic shock and even death may occur in some cases.

3. Local reaction: redness, swelling and pain may appear at the injection site and subside after several days. A large dose of intramuscular injection can cause severe large area aseptic necrosis in the injection area, resulting in toxemia and even death. Acupoint injection can cause muscle atrophy and joint dysfunction.

matters needing attention

1. Do not mix injection with any other drugs. 2. Analgin is generally not the first choice of medication, but only used in the case of acute high fever, severe illness and no other effective antipyretic drugs available. 3. In case of occasional sweating and collapse during injection, attention should be paid to observation and treatment, and the dosage should be strictly controlled. 4. Regular blood examination during medication. In case of granulocytopenia, the drug should be stopped immediately and antibiotics should be applied in time to prevent infection.