Is hydatidiform mole a man's problem?

Update Date: 2022-06-08 Source: Network

summary

Hydatidiform mole is an abnormal pregnancy in which there is only placenta but no fetal growth in the womb. According to the naked eye, microscope, karyotype and clinical manifestations, the hydatidiform mole can be divided into complete hydatidiform mole and partial hydatidiform mole. Is hydatidiform mole a man's problem? Let's talk about it

Is hydatidiform mole a man's problem?

Complete grape: it may be related to region, race, nutrition, socio-economic factors and gestational age. The karyotype of complete hydatidiform mole is 46XX. It is a diploid formed by a haploid sperm fertilized by an empty egg with missing or inactivated nuclear genetic material. Another 10% of them have a karyotype of 46XY, which is a combination of an empty egg and two haploid sperm (23x and 23y) during fertilization.

Partial hydatidiform mole: may be related to the use of oral contraceptives and menstrual disorders. More than 90% of them are triploids. The extra set of chromosomes usually comes from the father and is fertilized by one normal haploid egg and two normal haploid sperm. Or by a normal haploid egg (sperm) and a meiotic failure of the diploid sperm (egg) fertilization.

Cytogenetic and pathological studies showed that the two types of hydatidiform mole had their own genetic characteristics. Complete hydatidiform mole chromosome genome is paternal origin, that is, the egg in the absence of egg pronucleus or inactivation of egg pronucleus and spermatogonium after the combination of development. In addition, cytogenetic studies have shown that most partial hydatidiform moles are of bisexual origin and have more paternal chromosomes.

matters needing attention

1. Smoking and drinking should be prohibited before pregnancy, so as not to affect the growth and development of the baby in the future. 2. Before pregnancy husband and wife do a comprehensive examination, if there is a disease must be cured before pregnancy. 3. More exercise, improve immunity, pay attention to the combination of work and rest.