Zoe syndrome symptoms?

summary

The so-called Zhuo AI syndrome, in fact, refers to gastrinoma, this gastric disease harm is very big, patients must take effective measures to control, if the development is serious, patients may appear gastric perforation, gastrointestinal bleeding, especially the most prone to gastric ulcer, then Zhuo AI syndrome patients will appear what symptoms? Come and study with me.

Zoe syndrome symptoms?

First: Zhuo AI syndrome, also known as gastrinoma, is characterized by refractory or unusual peptic ulcer, high gastric acid secretion, and non-invasive gastric cancer β Clinical syndrome characterized by islet cell tumor. The most common clinical manifestation is peptic ulcer, which is seen in 90% - 95% of patients with gastrinoma. Its clinical symptoms are often similar to those of ordinary peptic ulcer patients. It is caused by gastric antrum G cell proliferation or gastrin secreting tumor. Its characteristics are multiple and refractory peptic ulcer of upper digestive tract caused by hypergastrinemia and large amount of gastric acid secretion.

Second: zhuo'ai syndrome, also known as gastrinoma, is characterized by increased gastric acid secretion, which leads to gastric ulcer and gastric bleeding. Usually, gastric acid secretion test, serum gastrin determination, ultrasound, CT and other examinations can be used for diagnosis. H2 inhibitor can be used for treatment to inhibit gastric acid secretion. For gastrinoma, surgical resection should be considered.

Third: the typical clinical manifestation is aggressive peptic ulcer, accompanied by ulcers occurring in atypical sites (up to 25% of which are located below the duodenal bulb) or after surgery considered as benign peptic ulcer. In 25% ~ 40% of cases, the symptoms may be diarrhea, perforation, bleeding and obstruction. These complications may occur frequently and are life-threatening. However, the clinical manifestations, X-ray and endoscopic findings of more than 50% of patients are difficult to distinguish from common peptic ulcer

matters needing attention

Total gastrectomy may be required, and although there are few nutritional complications, patients need vitamin B12 100 per month μ In patients with metastasis, chemotherapy with streptozocin and adriamycin can reduce tumor volume (in 50% - 60% of patients) and serum gastrin concentration. It is an effective adjuvant therapy for omeprazole or total gastrectomy. Chemotherapy is ineffective for patients with metastasis.