What causes chronic nephritis

summary

I'm still in good health. Occasionally, I have a cold and fever. This year, I always feel weak and urinate abnormally. I often feel depressed, but I can't urinate much. My thigh is often very swollen. I found that I have chronic nephritis when I did the physical examination. Many of my patients questioned the cause of nephritis. Let's analyze it ！

What causes chronic nephritis

First of all, there is more than one cause of nephritis. Chronic nephritis is an immune disease due to infection, which causes damage to the internal environment and immune balance disorder. Its etiology and pathology is not a single kidney disease, but a series of diseases of the whole body.

Secondly, the disease of nephritis has a certain relationship with the immune system of the human body. Due to the disorder of immune balance, the kidney is diffuse on both sides, and a few of them are focal segmental mesangial proliferation, membrane proliferation, membranous, small lesions, focal sclerosis. In the late stage, most glomeruli are fibrotic or glassy, the glomerular cortex becomes thinner, and the glomerular capillaries atrophy. Finally, the majority of nephrons disappear, and the kidney is damaged The volume of the kidney shrinks and even becomes a shrunken kidney.

Finally, the cause of most glomerulonephritis is unknown. Chronic glomerulonephritis is a group of glomerular diseases with multiple causes. However, the etiology of chronic glomerulonephritis in most patients is unknown, and there is no clear relationship between chronic glomerulonephritis and Streptococcus infection. According to statistics, only 15% - 20% of the patients have changed from acute glomerulonephritis to acute glomerulonephritis. However, because the subclinical type of acute glomerulonephritis is not easy to be diagnosed, the actual percentage may be higher.

matters needing attention

When we find kidney disease, we often lose confidence in our own body, but we need to insist on treatment. When we find that the renal function is slowly declining, in addition to drug treatment, doctors usually recommend patients to reduce protein intake, so as to reduce the burden of the kidney and delay the time of becoming end-stage renal disease. In addition to limiting protein, doctors also choose to limit sodium according to the different conditions Or phosphorus or water diet.