Symptoms of sacrococcygeal chordoma

summary

Many patients are trapped by chordoma and require them to pay enough attention to the treatment of the disease. For example, Nini in today's wechat headline is a 7-year-old patient with chordoma. In order to help more people have a clear understanding of the disease and make a correct choice, we must do a good job in the treatment of the disease, So how does chordoma form?.

Symptoms of sacrococcygeal chordoma

First, chordoma originated from residual chordate tissue of embryo. During the embryonic period, the upper end of the notochord is distributed in the sphenoid and occipital bones of the skull base. Part of the notochord reaches the intracranial surface and connects with the dura above the sella turcica. The occipital part can reach below the bone (that is, the glossopharyngeal surface), and a part can also be located between the skull base and the pharyngeal wall. The lower end of the notochord is distributed in the central and paracentral parts of the sacrococcygeal region. Therefore, chordomas are more common in these areas, especially in the sphenoidal occipital part of skull base and sacrococcygeal part, followed by spinal type.

Second, chordoma of skull base or chordoma of clivus belongs to the category of brain neurosurgical diseases. It belongs to low-grade malignant osteogenic tumor histologically, and has the following malignant characteristics: deep location, easy to invade the brain and important nerves and blood vessels; Most of them had no obvious capsule; Occasionally, it can be transferred; It is not easy to remove completely, and it is easy to recur after operation.

Third, the median survival time of chordoma was 6-28 months. That is to say, if chordoma is found and not treated, half of the patients will be life-threatening in 6-28 months, indicating that chordoma is very dangerous. Once found, it should be actively treated, and some early and limited chordomas may be cured by surgery.

matters needing attention

Early reports at home and abroad showed that the survival rate of chordoma in skull base was generally low, and the 5-year survival rate was maintained at 30% - 40%. In recent years, the relevant reports at home and abroad are increasing gradually. The postoperative survival rate of skull base chordoma has been significantly improved, and the 5-year survival rate is maintained at 60% - 70%. It is generally believed that the more thorough the tumor resection, the better the prognosis of patients. Different neurosurgical centers adopt different techniques, resulting in different resection rates.