Three week symptoms of HIV infection?

summary

The average incubation period of AIDS is 9 years, which can be as short as several months and as long as 15 years. From the initial infection of HIV to the end stage, it is a relatively long and complex process. In different stages of the whole process, HIV related clinical manifestations are diverse. According to the standards and guidelines for the diagnosis and treatment of AIDS in China, AIDS is divided into acute stage, asymptomatic stage and AIDS stage.

Three week symptoms of HIV infection?

It usually occurs in 2-4 weeks after the initial infection of HIV, and some infected people have clinical symptoms caused by HIV viremia and acute damage of immune system. The clinical symptoms of most patients were mild, lasting for 1-3 weeks and then relieved. Fever is the most common clinical manifestation, accompanied by general discomfort, headache, night sweats, nausea, vomiting, diarrhea, sore throat, myalgia, arthralgia, rash, lymphadenopathy and nervous system symptoms. HIV RNA and p24 antigen could be detected in serum of this stage. HIV antibody did not appear until a few weeks after infection. The ratio of CD4 / CD8 is inversed. Some patients may have mild leukopenia and / or thrombocytopenia or abnormal liver function.

It can enter this phase from acute phase, or directly enter this phase without obvious symptoms of acute phase. The duration of this period is generally 6-8 years, which is related to the number, type, route of infection, individual differences in immune status, nutrition and health conditions, living habits and other factors. At this stage, due to the continuous replication of HIV in infected people, the CD4 + T lymphocyte count gradually decreased, which is infectious.

It is the final stage after HIV infection. The CD4 + T lymphocyte count of the patients decreased significantly, more than 200 / mm3, and the HIV plasma viral load increased significantly. The main clinical manifestations were HIV related symptoms, opportunistic infections and tumors.

matters needing attention

Respiratory system: Pneumocystis pneumonia (PCP) caused by human Pneumocystis jiroveci is characterized by chronic cough, fever, cyanosis and decreased blood oxygen partial pressure. There are few pulmonary rales. Chest X-ray showed interstitial pneumonia. The results showed that Pneumocystis could be quickly detected by hexamethylenetetramine silver staining or modified methylene blue staining in sputum or bronchoalveolar lavage fluid. CMV, MTB, Mycobacterium avium complex (MAC), Candida and Cryptococcus often cause pulmonary infection.