The harm of chronic renal failure

summary

I had some red pimples on my body, itching very much. My bare feet seemed to be a little swollen. Three months ago, I had a routine urine test and renal function test, and found that it was renal failure. For patients with this disease should be treated as soon as possible, I will tell you about the harm of chronic renal failure.

The harm of chronic renal failure

Hazard 1: the residual nephron in patients with renal failure increases the glomerular filtration rate to compensate for the loss of functional nephron, which excretes metabolic waste in the body. However, due to the increased load of residual nephron, it further accelerates the glomerular damage, such as causing glomerular hypertrophy.

Harm 2: increased secretion of ammonia in renal tubules, which can reduce the occurrence of acidosis in patients with chronic renal failure, but accelerate the damage of renal tubulointerstitium.

Harm 3: the patient's glomerular interstitial inflammatory cells infiltrate, which can phagocytize and remove the harmful substances causing glomerular and tubular damage, but it can also release growth factors and inflammatory mediators, stimulate the deposition of collagen and increase of mesangial matrix, leading to glomerulosclerosis and tubulointerstitial fibrosis.

matters needing attention

Patients need to pay attention to their own diet. Generally, those foods with high purine content should not be eaten. For example, animal viscera and seafood should not be eaten. Moreover, a small amount of meat can be eaten. Don't eat too much at a meal. Generally, vegetarianism is the most important.