What reason does infantile Keshan disease have

summary

Keshan disease in children is a kind of endemic cardiomyopathy with myocardial injury. The etiology is still unclear. The main clinical manifestations were acute or chronic heart failure with various arrhythmias. The disease is more common in rural areas. The occurrence of Keshan disease is related to biogeochemical factors. Selenium deficiency may be the basic pathogenic factor of Keshan disease, but it is not the only one. Keshan disease is a natural focus disease with epidemic trend, which is consistent with the characteristics of virus infection, but lack of basis. So, what are the causes of Keshan disease in children? Now I'll introduce it to you

What reason does infantile Keshan disease have

Selenium deficiency caused Keshan disease. In some areas, the chemical analysis of water quality, soil and grain and the analysis of selenium in patients are lower than those in non disease areas; Feeding animals with water and grain in the disease area can cause myocardial lesions similar to Keshan disease; Healthy people can get sick after entering the ward for 3 months, and the symptoms can be alleviated or disappeared after leaving the ward; It is effective to improve the diet of the people in the ward and to prevent the disease with selenium salt.

Keshan disease in children caused by lack of nutrients in diet. The deficiency of some amino acids and vitamins in nutrients may be involved in the pathogenesis of Keshan disease. The content of vitamin E in the population of high incidence area is low, and the antioxidant capacity is decreased, which may be related to the incidence of Keshan disease.

Immune injury is also a cause of Keshan disease in children. IgG deposition was found in myocardial biopsy and autopsy samples of Keshan disease. Anti myocardial antibody and antinuclear antibody could be detected in serum of Keshan disease, and the titer of immune complex increased significantly, suggesting that immune injury may be related to the pathogenesis of Keshan disease.

matters needing attention

Keshan disease in children is a kind of endemic cardiomyopathy with myocardial injury. The etiology is still unclear. The main clinical manifestations were acute or chronic heart failure with various arrhythmias. The disease is more common in rural areas.