Why is kidney cancer asymptomatic?

summary

Renal cell carcinoma (RCC) is a malignant tumor originated from the renal parenchymal urothelial system. It is also known as renal adenocarcinoma. It includes various subtypes of renal cell carcinoma originating from different parts of urinary tubules, but does not include tumors originating from renal interstitium and renal pelvis. As early as 1883, German pathologists, based on the microscopic observation that the shape of cancer cells is similar to adrenal cells, put forward the theory that renal cancer is the origin of adrenal tissue remaining in the kidney. Therefore, before the reform and opening up in China, renal cancer was called Z tumor or adrenal like tumor. Let's have a look.

Why is kidney cancer asymptomatic?

The clinical diagnosis of renal cell carcinoma mainly depends on imaging examination, and the final diagnosis needs pathological examination. B-ultrasound is the simplest way to screen renal cancer without any harm to the body. Now the level of examination is constantly improving, and some renal tumors of 1-2 cm can also be found, so patients can make further examination accordingly. The commonly used imaging examinations include abdominal CT, abdominal MRI, chest X-ray (anteroposterior and lateral) and so on.

Due to the hidden location of the kidney, lack of typical clinical manifestations in the early stage, renal cell carcinoma with symptoms is often in the advanced stage. In recent years, the majority of patients with renal cell carcinoma are asymptomatic renal cell carcinoma found in the health examination, these patients account for more than 50% - 60% of the total number of patients with renal cell carcinoma. Low back pain and hematuria are the most common symptoms in patients with symptomatic renal cancer, and a few patients come to hospital with abdominal mass. Some patients also accompanied with hypertension, anemia, weight loss, fever, polycythemia, liver dysfunction, hypercalcemia, hyperglycemia and so on. If the tumor metastasis, may also appear bone pain, fracture, cough, hemoptysis and other symptoms.

Renal cell carcinoma (RCC) is a malignant tumor originated from the renal parenchyma and urinary tubular epithelial system, accounting for 2% - 3% of adult malignant tumors. At present, the incidence rate is around 6.0/10 million, and about 78 thousand of new patients are in the country every year. Of them, 25% are advanced patients, and males are higher than females. The highest incidence is 50~70 years old. The etiology of renal cancer is complex. According to epidemiological investigation, some renal cancer is related to smoking, obesity, hypertension, kidney disease, some industrial substances, aflatoxin, hormone and radiation. In addition, there are some genetic factors.

matters needing attention

In terms of treatment, the most important is surgical treatment. In recent years, there are also targeted drug therapy. Because everyone's basic state, physical state, and tumor location, size, nature, benign and malignant state are different, doctors need to be different from person to person for comprehensive treatment. It should be pointed out that in addition to strictly following the doctor's advice and carrying out targeted treatment as soon as possible, pathological examination of nuclear grading system should also be carried out as soon as possible. It is the most widely used nuclear grading system for renal cell carcinoma at present, and it is also one of the independent indicators widely recognized for judging the prognosis of renal cell carcinoma, The higher the grade, the higher the risk of recurrence. The 3-year survival rate and cancer specific survival rate were significantly lower. Therefore, for patients with higher nuclear grade, close follow-up should be carried out in order to find metastasis early and strictly follow the doctor's advice, so as to obtain better treatment effect.