Giant cell symptoms of intrauterine infection?

summary

Intrauterine infection, also known as congenital infection or mother to child transmission disease, refers to the intrauterine infection of the fetus caused by infection during pregnancy. The main route of intrauterine infection is vertical transmission of pathogenic microorganism to fetus through placenta; The retrograde diffusion of pathogenic microorganisms in the lower genital tract of pregnant women; Perinatal infection during delivery. Giant cell symptoms of intrauterine infection? Let's talk about it.

Giant cell symptoms of intrauterine infection?

It is one of the important ways of human cytomegalovirus infection. 90% of the infected fetuses are recessive infection, only 10% of them are clinical infection, but sometimes the consequence is more serious.

Acquired infection of cytomegalovirus in infants, mostly recessive infection or mild symptoms, but the clinical manifestations of a few patients are more serious, perinatal infection of neonatal patients, some of them may be intrauterine infection, can be persistent pneumonia, children and adult patients can develop cytomegalovirus hepatitis.

Ganciclovir and foscarnet sodium are two kinds of antiviral drugs for the treatment of CMV infection. They have been used in the treatment of AIDS patients, patients with CMV infection after organ transplantation, or prophylactic drugs after organ transplantation, but the clinical effect is not very ideal.

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Cytomegalovirus mainly invades epithelial cells. The main organs (lung, liver, brain, kidney, spleen, heart, intestine), glands (salivary gland, gonad) and nervous system can be involved. The infected cells degenerated, increased in size, presented as giant cells, and then disintegrated, leading to local necrosis and inflammation.