What are the strict conditions for bone marrow transplantation

summary

Leukemia, for patients, is a disaster. They feel that their lives have come to an end. In fact, medicine is so developed now that many experts study the use of bone marrow transplantation to alleviate leukemia. Let's talk about the strict conditions for bone marrow transplantation.

What are the strict conditions for bone marrow transplantation

First, patients should do a series of blood and bone marrow examination before transplantation to determine the disease diagnosis, type and disease status, so as to determine the appropriate pretreatment scheme, monitoring of primary disease after transplantation and appropriate intervention strategy. At the same time, it is advisable to choose the donors with identical HLA matching, between 8 and 60 years old, in good health, without severe gravity, lung, liver, kidney, brain and mental diseases, and with normal hematopoietic and immune system functions.

Second: the use of pretreatment programs can create space, immunosuppression and disease clearance. Therefore, there are many kinds of pretreatment schemes to choose. The intensity of pretreatment for non myeloablative transplantation decreased. If there is no exogenous hematopoietic stem cell support, the hematopoietic system will recover within 3 months.

Thirdly, one of the key factors of non myeloablative hematopoietic stem cell transplantation is that the intensity of radiotherapy (chemotherapy) is significantly lower than that of traditional regimen. There are three main sources of hematopoietic stem cells for transplantation: bone marrow, peripheral blood hematopoietic stem cell collection and umbilical cord blood. After proper treatment, it was reinfused to the patients after pretreatment. If there is no support of exogenous hematopoietic stem cells in myeloablative transplantation, the intensity of myeloablative transplantation will make the hematopoietic system unable to recover within 3 months.

matters needing attention

The most important thing of bone marrow transplantation is to have matching bone marrow. However, many patients do not wait for matching bone marrow and can only receive chemotherapy to maintain their lives. Many patients do not wait for matching bone marrow and lose their lives. This is also a cruel reality and the most stringent condition.