How is meningioma formed? Congenital and genetic factors

summary

The cause of meningioma is still unclear, but studies have shown that the occurrence of meningioma may be related to the following factors: how is meningioma produced? Meningioma is a kind of meningeal endothelial cell tumor, which is a common benign tumor, but also a very important tumor in the orbit. It is more common in middle-aged people, women for men. So, do you know how meningiomas come into being?

How is meningioma formed? Congenital and genetic factors

Reason 1: congenital and genetic factors. The occurrence of meningioma may be related to genetic factors. In the process of embryonic development, some cells or tissues can stop growing and remain in the brain, which has the potential of differentiation and can develop into brain tumors. The common ones are craniopharyngioma, chordoma, teratoma, epithelioid and dermoid cyst. How does meningioma come into being? These congenital residual embryonic cells mutate under the action of virus, radiation and carcinogenic chemicals, and then develop towards cancer, eventually leading to meningioma.

Second, biological factors. Biological factors are also one of the important causes of meningioma. It has been proved that viruses (such as adenovirus, simian vacuolar virus (SV40), sarcomavirus, etc.) can induce intracranial tumors in birds and vertebrates. The virus inserted into the cell's chromosome, changed the characteristics of chromosome genes, changed the original characteristics of cell proliferation, and led to the occurrence of meningioma. Therefore, biological factors are also one of the causes of meningioma.

The third reason is chemical factors. How is meningioma produced? Related factors of meningioma also include chemical factors. Animal experiments have proved that a variety of chemicals can induce brain tumors (various gliomas, meningiomas, sarcomas, epithelial cancers, pituitary adenomas, etc.), such as methylcholanthrene, diphenylanthracene, benzo ratio, n-nitrous acid compounds, etc.

matters needing attention

Meningioma is closely related to physical factors. Experts pointed out that research data show that radiation can induce skin, lip, tongue, esophageal cancer. In animal experiments, it is found that radiation can cause interstitial transformation (canceration), and the mechanism is that radiation can cause oncogene mutation in intracranial fibroblasts or meningeal endothelial cells, resulting in canceration of cells.