What is ankylosing spondylitis

summary

My grandfather had back pain and fever last year. Later, he got ankylosing spondylitis. So, what is ankylosing spondylitis? Let's talk about it.

What is ankylosing spondylitis

Firstly, ankylosing spondylitis (as) is a disease with the main symptoms of sacroiliac joint and spinal attachment point inflammation. It was strongly associated with HLA-B27. Some microorganisms, such as Klebsiella pneumoniae, have common antigens with their own tissues, which can induce abnormal immune response. It is a chronic inflammatory disease characterized by fibrosis and ossification of large joints of limbs, annulus fibrosus of intervertebral disc and its adjacent connective tissue, and ankylosis of joints.

Secondly, ankylosing spondylitis belongs to the category of rheumatism, is a kind of serum negative spondyloarthropathy. The etiology of the disease is still unclear. It is a chronic disease with the spine as the main lesion site, involving the sacroiliac joint, causing spinal ankylosis and fibrosis, causing varying degrees of eye, lung, muscle and bone lesions. It is an autoimmune disease.

Finally, for young people aged 16-25, especially young men. Ankylosing spondylitis generally occult onset, early may not have any clinical symptoms, some patients in the early may show mild systemic symptoms, such as fatigue, emaciation, long-term or intermittent low fever, anorexia, mild anemia and so on. As the disease is mild, most patients can not be found early, resulting in delay of the disease and loss of the best opportunity for treatment. And patients will have varying degrees of joint pain or stiffness, generally mainly at night when the pain is more severe.

matters needing attention

The disease of ankylosing spondylitis should be treated in time after getting sick, and prevention is the main method in peacetime. Don't have too heavy load, and try to use the hard bed when sleeping.