How to check urinary protein

summary

I've been in a bit of a bad health recently. After listening to some of my recent symptoms, my doctor friend asked me to go to the hospital to check the urine protein. How to check urinary protein? Here is my experience when I went to the hospital for inquiry:

How to check urinary protein

How to check urinary protein? Urine protein qualitative test is a method for screening and rough estimation of urine protein content. There are three test methods: test paper method, sulfosalicylic acid method and heating acetic acid method. Both sulfosalicylic acid method and heating acetic acid method are based on the turbidity reaction, and the turbid or precipitated ones are regarded as negative (1), while the turbid or precipitated ones are regarded as positive (+). Sulfosalicylic acid method is simple, sensitive and can be widely used in general survey, but its sensitivity to white protein is higher than globulin, and there are many influencing factors, which are easy to cause false negative or false positive. The sensitivity of heating acetic acid method to albumin and globulin is basically the same, with few influencing factors and high accuracy.

How to check urinary protein? According to the turbidity reaction, the content of urinary protein is estimated as follows: urinary protein < 0.1 g / L: 1; urinary protein 0.1-0.2 g / L: ±; urinary protein 0.2-1.0 g / L: + +; urinary protein 1.0-2.0 g / L: + + +; urinary protein 2.0-4.0 g / L: + + + +; urinary protein > 4.0 g / L: + + + +. Normal urine contains trace protein (24-hour urinary protein < 150mg), which can not be detected by ordinary detection method, and the test result is negative. Beyond this range can be detected, known as proteinuria. However, because the urine protein test is only the result of measuring urine once, it is easily affected by the degree of urine concentration and dilution, and often can not accurately reflect the degree of proteinuria.

How to check urinary protein? When the glomerulus and renal tubules have pathological changes, such as glomerulonephritis, nephropathy and hypertension, proteinuria can occur; various bacterial infections, such as pyelonephritis, renal tuberculosis, septicemia, etc., can also occur proteinuria; non infectious diseases, such as kidney stones, polycystic kidney, renal amyloidosis and shock, severe muscle injury, fever, jaundice, thyroid disease Glandular hyperfunction, hemolytic anemia and leukemia, also can appear proteinuria. Physiological proteinuria is common after eating high protein diet, mental excitement, strenuous exercise, long-term cold, pregnancy, etc., may appear temporary proteinuria, but the qualitative of urinary protein is generally not more than +.

matters needing attention

Generally speaking, persistent proteinuria often represents kidney disease. The amount of urine protein reflects the degree of the disease, and the clinical curative effect can be observed according to it. However, it should be pointed out that in the late stage of glomerulopathy, due to a large number of nephron depletion, protein filtration is reduced, but urine protein examination is reduced or disappeared, which does not represent the reduction of renal disease. One check out no problem does not mean that the follow-up no problem, so under the guidance of the doctor, or suggest regular review is better.