How to treat congenital adrenal hyperplasia

summary

What we call congenital adrenal hyperplasia is that most of the patients with adrenal gland secretion of glucocorticoid, desalting hormone is insufficient, and androgen is too much, so there are different degrees of adrenocortical dysfunction, accompanied by masculinization of girls, while boys show precocious puberty. How to treat congenital adrenal hyperplasia? Let's share it with you

How to treat congenital adrenal hyperplasia

First: glucocorticoid replacement therapy: GC is the main treatment for various types of CAH. Its main role is to inhibit ACTH, reduce the androgen levels of 21-OHD, 11 β - OHD and 3 β - HSD deficiency, and reduce the deoxycortisol (DOC) levels of 11 β - OHD and 17 α - OHD, so as to improve the bone age, final height or hypertension of these patients, and enhance the stress ability of patients.

Second: replacement therapy with mineralocorticoid: mineralocorticoid is mainly used to treat patients with 21-OHD, 3 β - HSD deficiency and star deficiency, but most of the children with mineralocorticoid deficiency (especially 21-OHD) "salt loss" symptoms can be alleviated with age, and the treatment with mineralocorticoid can also be stopped.

Third: replacement therapy with mineralocorticoid: mineralocorticoid is mainly used to treat patients with 21-OHD, 3 β - HSD deficiency and star deficiency, but most of the children with mineralocorticoid deficiency (especially 21-OHD) "salt loss" symptoms can be alleviated with age, and the treatment with mineralocorticoid can also be stopped.

matters needing attention

If the treatment is timely and appropriate, the effect is good, and normal growth, development and fertility can be obtained. Monitoring during treatment is very important,