What is the principle of skin transplantation

summary

Because of my work, one of my colleagues suffered from severe burns. When I solved the problem, it involved skin transplantation. I was worried about the effect of the treatment. Everyone was very concerned about the principle of this method. Let's take a look at the principle of skin transplantation.

What is the principle of skin transplantation

First of all: under hyperbaric oxygen, the increase of oxygen partial pressure and oxygen storage in the tissue can enhance the growth vitality of the skin tissue, promote the growth of granulation tissue, reduce wound exudation and bacterial infection, make the wound fresh and clean, and create good conditions for skin inhibition.

Secondly, before the blood circulation between the skin graft or flap and the recipient area is established, hyperbaric oxygen in the tissue can reduce the continuous hypoxic state caused by the lack of blood supply of the skin graft, which is very conducive to the survival of the skin graft.

Finally, the ability of cell division and proliferation is closely related to the oxygen partial pressure in the tissue. When the oxygen partial pressure of extracellular fluid was lower than 1.3 kPa (10 mmHg), the cells no longer divided and synthesized collagen fibers. Under hyperbaric oxygen, the oxygen partial pressure around cells increased, cells became active, collagen and new capillaries were produced, which promoted the establishment of blood circulation. The blood circulation established between the skin graft and the recipient area can supply sufficient blood and oxygen to the skin graft or flap, which is helpful to improve the survival rate of the skin graft.

matters needing attention

It is necessary to observe closely after transplantation to check whether there are blood circulation disorders, secondary bleeding or inflammation and infection. These are common complications, which directly affect the effect of transplantation. Once they appear, they should be solved in time.