What are the reasons for high creatinine

summary

A few days ago, our company organized a physical examination once a year. During the physical examination, I found that my creatinine was high. Before, I didn't have this kind of situation during the physical examination. I don't know how and why the creatinine was high this time. Now let's take a look at the causes of high creatinine.

What are the reasons for high creatinine

First, the reason of high surface blood creatinine is that the kidney is damaged and the kidney can't urinate, while the reason of high real blood creatinine is that the inherent cells of the kidney are damaged and fibrosis occurs after the kidney is invaded by various causes. First, the phenotype transformation of the damaged renal intrinsic cells, the formation of pathological changes, stimulate the transformation of fibroblasts into myofibroblasts in the kidney, and at the same time, the invasion and stimulation of the inherent normal renal tissue, the occurrence of the same lesions, thus forming a kidney from the point to the surface, from the local to the whole, expanding the excitation type spread process.

Second: the original renal insufficiency, such as co infection, including cold, pneumonia, intestinal infection, urinary tract infection, etc., can appear in the short term blood creatinine rise. If the body loses water, such as fever, hyperhidrosis, decrease of drinking water, blood concentration during polyuria, decrease of renal blood flow, increase of serum creatinine can occur. Patients with original kidney disease, the use of drugs that damage the kidney, blood creatinine can be increased, or even irreversible.

Third: Patients with original kidney disease, due to the recurrence of the disease, oliguria, or even no urine phenomenon, can be combined with acute renal insufficiency, leading to increased serum creatinine. Fatigue, poor rest and inattention to life details can also cause transient elevation of serum creatinine. The original hypertension, blood pressure is not well controlled, long-term moderate and large amount of proteinuria (24-hour total urine protein is more than 1 g or even 1.5 g), can slowly progress, and the blood creatinine increases unconsciously.

matters needing attention

The cause of high creatinine is generally due to kidney problems. Some people with renal insufficiency are more likely to have high creatinine if they have a cold or infection. At this time, we should control it in time, pay attention to diet, have more rest and keep a happy mood.