Early symptoms of gastrinoma?

summary

Persistent and progressive abdominal pain, acid regurgitation, belching, salivation, nausea, vomiting and emaciation. Although most gastrinomas are malignant, the tumor itself rarely causes obvious symptoms because of its small size and slow development. Until the late stage of the disease, the symptoms of malignant tumor infiltration appear. Its clinical manifestation is mainly related to a large amount of gastric acid secretion. Let's take a look at the following.

Early symptoms of gastrinoma?

First: due to peptic ulcer, there may be a family history of peptic ulcer. This is due to gastrin strong and continuous stimulation of gastric mucosa, resulting in a large amount of gastric acid and pepsin secretion. Ulcers are usually single or multiple, with a diameter of less than 1 cm and a few more than 2 cm.

Second: patients may have diarrhea. Some cases of diarrhea can occur when the ulcer, the disease can be the first symptom or the only symptom. A few patients had diarrhea but no ulcer. Diarrhea often presents as massive, watery and fatty diarrhea.

Third, some patients may have other endocrine tumors. The distribution of endocrine glands involved was parathyroid gland, pancreas, pituitary gland, adrenal gland and thyroid gland. There were corresponding clinical manifestations related to endocrine gland hyperfunction.

matters needing attention

10-30 times a day. Severe cases can produce water and electrolyte disorders, and dehydration, hypokalemia and metabolic acidosis and other symptoms.