Symptoms of gestational nephropathy

summary

Gestational kidney disease refers to the renal lesions induced by pregnancy, such as pyelonephritis, acute renal failure during pregnancy, postpartum idiopathic acute renal failure and pregnancy induced hypertension syndrome. Pregnant women have a variety of physiological changes in renal function and hemodynamics, which may cause pathological damage to the kidney and renal dysfunction, especially in women with original kidney disease. If they do not actively prevent it, it may cause the recurrence and aggravation of the primary disease, and endanger the fetus. Let's know about the symptoms of gestational nephropathy

Symptoms of gestational nephropathy

Physiological changes during pregnancy can also lead to changes in renal function. From the second trimester of pregnancy, the renal blood flow and glomerular filtration rate of pregnant women increased by 30% - 50%, and continued to recover gradually after delivery. The average serum creatinine of normal pregnant women was 44-53 μ 5-0.6mg/dl, if serum creatinine is higher than 71-88 μ 8-1 mg / dl), which often indicates renal dysfunction. * pregnant women are prone to water and sodium retention, and about 20% of pregnant women can have a small amount of proteinuria. The basic pathophysiological changes of pregnancy induced hypertension syndrome are hypertension and organ damage caused by systemic arteriospasm. The renal blood flow and glomerular filtration rate decreased, and the permeability of glomerular capillary wall increased in hypoxia. Severe ischemia of renal parenchyma may lead to glomerular and tubular damage until renal cortex necrosis.

The clinical manifestations were moderate hypertension, proteinuria and edema. About 1 / 3 cases can be manifested as nephrotic syndrome, which is non selective proteinuria. Severe cases may have preeclampsia, eclampsia and acute renal failure.

Acute renal failure during pregnancy: it usually occurs in the first 3 months and the last 3 months of pregnancy. The peak of early stage is 10-12 weeks, which mainly occurs in septic abortion and a few secondary to hyperemesis gravidarum. In the late stage, the peak was 34-40 weeks, which was mainly caused by preeclampsia and eclampsia of pregnancy induced hypertension syndrome. The second was obstetric complications such as placental abruption, amniotic fluid embolism and massive hemorrhage. A few were acute fatty liver in pregnancy.

matters needing attention

It is suggested to go to the hospital for further treatment: in the early stage of kidney disease, in order to control the disease and not affect the renal function, insulin should be actively used; The second measure is to control the patient's blood pressure. Hypertension is another very important factor that aggravates diabetic nephropathy. Therefore, the patient should have a light diet, less salt, use antihypertensive drugs and quit smoking.