What injection does girl precocious puberty hit
summary
Girls have precocious puberty. Girls begin to develop female characteristics before the age of 8, such as menarche. This kind of advanced development can be regarded as precocious puberty. Parents are also very worried about girls' precocious puberty. Now let's talk about the injection for girls' precocious puberty.
What injection does girl precocious puberty hit
First: medroxyprogesterone (medroxyprogesterone): for the most commonly used drugs, can inhibit the secretion of central gonadotropin, has a direct effect on the synthesis of sex hormones. It can make the developing mammary gland shrink, even degenerate to undeveloped state; leucorrhea decrease or disappear, menstruation stop; it has no inhibitory effect on the growth of bone, epiphysis early fusion. The main side effects were mild glucocorticoid effect, inhibition of ACTH and cortisol secretion, increase of food intake and weight, and risk of diabetes and hypertension. Dosage: 2 times / D, 5-10mg each time; if intramuscular injection, 100-200mg / m2, once every 1-2 weeks.
Second: chlormadinone acetate: it can antagonize the secretion of gonadotropin and androgen, and has less side effects than medroxyprogesterone. The dosage is 2-4mg / D, and the course of treatment depends on the curative effect. In recent years, GnRH analogues or GnRH agonists have been used in the treatment of idiopathic precocious puberty.
Third: cyproterone: it has the characteristics of anti androgen, anti gonadotropin and progesterone. Therefore, its disadvantages are similar to medroxyprogesterone ester, but it can inhibit ACTH secretion and reduce cortisol. The commonly used dosage is 70-100mg per square meter of body surface area per day, taken twice, or intramuscular injection of 100-200mg / m2 every 2-4 weeks.
matters needing attention
The treatment plan mentioned above is to inhibit girls' precocious puberty by injection. In daily life, there are many behaviors that easily lead to girls' precocious puberty. For example, the food they eat may contain too much hormone and make girls develop early. Therefore, parents should take this problem seriously.
