What are the causes of lupus nephritis

Update Date: 2022-06-01 Source: Network

summary

The incidence rate of lupus nephritis is mainly due to endocrine factors. I thought it would only lead to abnormal menstruation, and knowing the cause of the disease could reduce the incidence of lupus nephritis. Let's take a look at the causes of lupus nephritis.

What are the causes of lupus nephritis

One of the reasons: endocrine factors: lupus erythematosus mostly occurs in women of childbearing age, and there is almost no gender difference between children and elderly patients. Lupus erythematosus often occurs in male patients with testicular dysplasia. In lupus erythematosus patients, both men and women have increased estrone hydroxylation products. In NZB / NZW mice, the disease of female mice is more serious than that of male mice. Androgen treatment can alleviate the disease, while estrogen treatment can worsen the disease. It suggests that estrogen has an effect on the pathogenesis of lupus nephritis, which indicates that lupus nephritis is related to endocrine factors.

The second reason: genetic factors: heredity is an important factor in the pathogenesis of lupus erythematosus. People with genetic factors of lupus erythematosus will cause this disease once they encounter the inducing conditions in certain environments. According to the survey, black and Asian people are more than white people with lupus erythematosus. The incidence of family history of lupus erythematosus is as high as 5%-12%, and the incidence rate is 69%.

Third reason: environmental factors: experts point out that environmental factors are the factors that directly induce lupus erythematosus, including physical and chemical aspects. Physical factors such as ultraviolet radiation, chemical factors such as drugs, some drugs will aggravate the condition of lupus nephritis.

matters needing attention

Lupus nephritis patients in the cold season should pay attention to keep warm, winter go out to wear a good hat, mask, avoid cold, try to reduce cold and other infectious diseases, infection is easy to aggravate the condition of lupus nephritis.