What medicine does children adrenal cortex function not take?
summary
Adrenocortical insufficiency is caused by many congenital or acquired reasons, which leads to a series of clinical manifestations. Due to the different etiology and pathology, the clinical manifestations are quite different. The onset of the disease, the age of onset, the duration of the disease and the severity of the disease are obviously different. What medicine does children adrenal cortex function not take?
What medicine does children adrenal cortex function not take?
The causes of the disease, defects or lesions in any part of the hypothalamus pituitary adrenal axis, may lead to adrenocortical insufficiency, such as congenital hypophysis or hypophysis; ② Primary adrenal hypoplasia or hypoplasia; ③ Congenital defect of adrenocortical hormone synthesis; ④ Familial glucocorticoid deficiency; ⑤ Addison's disease: in children, adrenocortical dysfunction is caused by adrenal destructive lesions such as tuberculosis, histoplasmosis, coccidiosis, mycosis, amyloidosis and metastatic cancer, which is called Addison's disease; ⑥ Adrenoleukodystrophy; ⑦ Adrenal hemorrhage: hemorrhage may be caused by dystocia or asphyxia in neonatal period; ⑧ Warver syndrome; ⑨ Sudden withdrawal of corticosteroids or ACTH; ⑩ The simple deficiency of aldosterone synthesis is autosomal recessive inheritance; ⑪ Pseudohypoaldosteronism is autosomal recessive inheritance.
Common symptoms: feeding difficulties, loss of appetite, nausea, vomiting, anorexia, fatigue, abnormal body shape, nausea and vomiting, metal color or slate gray skin. The age and manifestation of symptoms vary according to the etiology. Clinical manifestations can be divided into three types: infant salt loss, chronic adrenocortical insufficiency and acute adrenal crisis.
To correct the disorder of water and electrolytes, 5% glucose saline should be infused immediately, measured at 20ml / kg, and rapidly infused intravenously within 0.5-1h, so as to raise blood pressure and improve circulation. The total amount of infusion was 80-120 ml / (kg · d). In the second 24 hours, hydrocortisone (cortisol) was reduced, and the infusion volume could be 60 ml / (kg · d). If necessary, add salt hormone, intramuscular injection of DOCA 1-5 mg / D, or fluhydrocortisone 0.05-0.1 mg / d. If the condition is still not improved, plasma can be injected, and blood transfusion can be used when there is bleeding. Intravenous drip can be stopped after 48 hours. In particular, newborns with adrenal insufficiency can die within a few days if they are not treated in time. During the infusion, excessive fluid volume should be prevented to avoid pulmonary edema or heart failure.
matters needing attention
Nursing care of patients with adrenocortical hypofunction. Supplement nutrition, drink more milk, supplement vitamin D, B vitamins, vitamin C, carotene and other nutrients, reduce the pressure of adrenal gland. Avoid the long-term mental burden caused by nervous tension, marital discord, bad workplace, illness, disrespect or loneliness. They are harmful to adrenal glands. Eat more fresh fruits and vegetables, especially green leafy vegetables. Beer yeast, brown rice, legumes, olives and whole grains are all healthy foods that can be added to the diet.
