Symptoms of diabetes insipidus without drinking water

summary

Secondary diabetes insipidus patients also have the symptoms and signs of primary disease. Because this disease often has complications, patients with traumatic CDI can be manifested as transient diabetes insipidus and triphasic diabetes insipidus. Triphasic diabetes insipidus can be divided into acute phase, intermediate phase and persistent phase. Let's learn about the problem of diabetes insipidus without drinking water.

Symptoms of diabetes insipidus without drinking water

First: polyuria and polydipsia: the prominent clinical manifestation of the disease. About 90% of hereditary cases occur in men. It can be manifested as polyhydramnios before birth and polyuria and polydipsia at birth. The main symptoms are polyuria (low specific gravity urine), thirst, polydipsia, growth and development disorders, etc. Severe patients showed high fever, convulsions, dehydration, hypernatremia and other clinical symptoms and corresponding manifestations. With the increase of age, the symptoms of this type can be gradually alleviated. Secondary patients first show the symptoms of primary disease, and then appear polyuria, thirst, dehydration, blood concentration and other corresponding symptoms and signs. Laboratory examination may have hypernatremia, hyperchloremia, etc.

Second: hypotonic urine: the specific gravity of urine is always lower than 1.005, or the volume of urine is lower than 200mosm / (kg H2O). If solute diuresis is given, it can only reach the level of isoosmotic 280-300mosm / (kg H2O) with plasma.

Third: hypertonic dehydration and hypovolemia: because infants can not express thirst, they are prone to hypertonic dehydration and hypovolemia, which can lead to central nervous system symptoms and infant intellectual development disorders. Severe water loss can lead to death. When dehydration is caused by factors other than CDI and NDI, the urine should be concentrated. Therefore, the possibility of infant dehydration with diluted urine should be noted. Severe hypertonic dehydration may also occur in adult patients with inappropriate water restriction or with central disturbance of osmolarity perception.

matters needing attention

1. Patients with diabetes insipidus should be given enough water during treatment to prevent water loss, potassium loss, and water poisoning caused by excessive drinking. 2. Patients should increase nutrition, eat less salt, avoid spicy food.